Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.55 |
| ▸ | KDM1A | O60341 | 11/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12523495 | 0.86 | HDAC6 (0.59) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL15341332 | 0.84 | POLB (0.56) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL12523493 | 0.84 | KDM1A (0.55) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL15341333 | 0.83 | OGA (0.46) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL17145408 | 0.83 | ALDH1A1 (0.52) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL13535031 | 0.80 | HDAC6 (0.52) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL26441680 | 0.80 | POLB (0.41) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL12395356 | 0.77 | HDAC6 (0.61) | HDAC6KDM1AHDAC1HDAC3HDAC2 | |
| SCHEMBL25447242 | 0.77 | CHRM4 (0.42) | — | |
| SCHEMBL13061212 | 0.77 | HDAC6 (0.60) | HDAC6KDM1AHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061368-A1 | HYDROXIMIC ACID DERIVATIVE AND USE THEREOF | 成都自豪药业有限公司 | 2023-04-20 | — | — | WO | disclosed |