SCHEMBL25159192

SCHEMBL25159192

C=C(C)C(=O)OCC(COc1ccc(C2(c3ccccc3)c3ccccc3-c3ccccc32)cc1)OC(=O)C(=C)C

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.38
POLB P06746 3/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PDK2 Q15119 2/20 0.34
MTNR1A P48039 3/20 0.33
MTNR1B P49286 3/20 0.33
ELANE P08246 1/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 3/20 0.32
KIF11 P52732 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
OPRK1 P41145 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9926774 0.98 AR (0.39) ARPOLBAPEX1HTTTDP1
SCHEMBL25159191 0.98 AR (0.39) ARPOLBAPEX1HTTTDP1
SCHEMBL16425280 0.94 AR (0.36) ARPOLBAPEX1HTTTDP1
SCHEMBL24525712 0.92 AR (0.39) ARPOLBAPEX1HTTTDP1
SCHEMBL16425357 0.89 THRB (0.34) ARPOLBAPEX1HTTTDP1
SCHEMBL16425354 0.89 THRB (0.36) ARPOLBAPEX1HTTTDP1
SCHEMBL16900327 0.89 AR (0.33) ARPOLBAPEX1HTTTDP1
SCHEMBL16900531 0.86 AR (0.32) AR
SCHEMBL18325962 0.85 PDK2 (0.33) ARPOLBAPEX1HTTTDP1
SCHEMBL4952710 0.85 POLB (0.43) POLBAPEX1HTTTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3959247-B1 LOW VISCOSITY CROSSLINKABLE COMPOSITIONS FOR COATINGS AND MATERIALS WITH A HIGH REFRACTIVE INDEX AND HIGH THERMAL DEFLECTION TEMPERATURE ARKEMA FRANCE (FR) 2023-04-19 EP disclosed