SCHEMBL25159461

SCHEMBL25159461

N#CC(C#N)=C1COc2cc(Cl)c(Cl)cc21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.34
▸ FLT1 P17948 1/20 0.31
▸ AHR P35869 1/20 0.31
▸ NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30306366 0.69 EGFR (0.34) EGFR
SCHEMBL26319499 0.69 EGFR (0.34) EGFR
SCHEMBL20819702 0.67 EGFR (0.35) EGFR
SCHEMBL29484391 0.67 EGFR (0.35) EGFR
SCHEMBL16357239 0.66 MAPT (0.42) FLT1AHRNOTUM
SCHEMBL10965188 0.61 NOTUM (0.35) FLT1AHRNOTUM
SCHEMBL24374958 0.60 GPR35 (0.34) —
SCHEMBL19410119 0.60 EGFR (0.61) EGFR
SCHEMBL8942751 0.58 GAA (0.41) EGFR
SCHEMBL17431036 0.58 MCL1 (0.33) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230121184-A1 ORGANIC SEMICONDUCTING COMPOUND AND THE ORGANIC PHOTOELECTRIC COMPONENTS USING THE SAME Raynergy Tek Incorporation (TW) 2023-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230121184-A1 ORGANIC SEMICONDUCTING COMPOUND AND THE ORGANIC PHOTOELECTRIC COMPONENTS USING THE SAME OCIAD2, OR10J3, OCIAD1 EGFR 3603/4885FLT1 4157/4885AHR 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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