Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860346 | 1.00 | PTGS1 (0.49) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL11351022 | 0.85 | CCR1 (0.52) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL10578770 | 0.84 | PTGS1 (0.45) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL1096675 | 0.84 | PTGS1 (0.49) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL7652207 | 0.84 | KMT2A (0.49) | KMT2A | |
| SCHEMBL29061992 | 0.84 | KMT2A (0.49) | KMT2A | |
| SCHEMBL27637858 | 0.83 | SGMS2 (0.45) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL10769339 | 0.81 | FFAR1 (0.54) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL31435877 | 0.80 | PTGS1 (0.49) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL11161903 | 0.80 | KMT2A (0.40) | MEN1KMT2ATDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064241-A1 | A MIXTURE OF PYRETHROIDS AND MILBEMYCINS AND USES THEREOF | VALENT BIOSCIENCES LLC (US) | 2023-04-20 | — | — | WO | disclosed |