SCHEMBL25162017

SCHEMBL25162017

Cc1ccc(C(C)(C)c2ccc(N)c(C)c2)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.48
CYP3A4 P08684 7/20 0.48
ALDH1A1 P00352 6/20 0.48
TDP1 Q9NUW8 6/20 0.48
TSHR P16473 2/20 0.48
ESR2 Q92731 2/20 0.46
AR P10275 1/20 0.46
MAPK1 P28482 1/20 0.42
KIF11 P52732 1/20 0.39
S100B P04271 1/20 0.38
CASP1 P29466 1/20 0.38
SKP2 Q13309 1/20 0.37
POLB P06746 1/20 0.37
RECQL P46063 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.36
ALOX15 P16050 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2385022 0.93 CYP3A4 (0.54) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL30295289 0.93 CYP3A4 (0.54) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL30806190 0.93 CYP3A4 (0.54) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL8119699 0.91 CYP3A4 (0.52) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL9064553 0.86 ESR1 (0.61) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL10447989 0.85 ESR1 (0.53) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL11301815 0.85 ESR1 (0.47) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL11020737 0.83 ESR1 (0.50) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL3937305 0.82 ALDH1A1 (0.52) ESR1CYP3A4ALDH1A1TDP1TSHR
SCHEMBL29437036 0.82 ALDH1A1 (0.52) ESR1CYP3A4ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119573-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2023-04-20 US disclosed