Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12224095 | 0.77 | RXRA (0.54) | RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL20756518 | 0.77 | RXRA (0.46) | RXRAGRIN1GRIN2BKCNH2NOTUM | |
| SCHEMBL25163608 | 0.75 | RXRA (0.43) | RXRAGRIN1GRIN2BKCNH2NOTUM | |
| SCHEMBL20468184 | 0.75 | NOTUM (0.72) | RXRAGRIN1GRIN2BKCNH2NOTUM | |
| SCHEMBL19211395 | 0.73 | NOTUM (0.70) | RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL19219465 | 0.72 | RXRA (1.00) | RXRAGRIN1GRIN2B | |
| SCHEMBL13180348 | 0.71 | RXRA (0.64) | RXRAGRIN1GRIN2BKCNH2NOTUM | |
| SCHEMBL23381114 | 0.70 | RXRA (0.41) | RXRAGRIN1GRIN2BKCNH2NOTUM | |
| SCHEMBL13255707 | 0.70 | NOTUM (0.54) | RXRAGRIN1GRIN2BKCNH2NOTUM | |
| SCHEMBL3777938 | 0.69 | NOTUM (0.68) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |