SCHEMBL251655

SCHEMBL251655

CCCCO[Si](O)(O)O.[NaH]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
ALDH1A1 P00352 2/20 0.39
ATM Q13315 1/20 0.36
CYP3A4 P08684 2/20 0.35
HPGD P15428 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
LMNA P02545 1/20 0.32
LTA4H P09960 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
NR5A1 Q13285 1/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76347 0.97
Rubidium SCHEMBL4811660 0.94 TSHR (0.40) TSHRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL28470868 0.94 TSHR (0.40) TSHRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL27916913 0.94 TSHR (0.40) TSHRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL4812719 0.94 TSHR (0.40) TSHRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL4808794 0.94 TSHR (0.40) TSHRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL29286190 0.94 TSHR (0.40) TSHRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL4810989 0.94 TSHR (0.40) TSHRADRB2ADRB1ADRB3ALDH1A1
SCHEMBL10631648 0.92 TSHR (0.39) TSHRADRB2ADRB1ADRB3ALDH1A1
Alcohol SCHEMBL28323340 0.92 TSHR (0.44) TSHRADRB2ADRB1ADRB3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108928823-B silicon dioxide aerogel and normal pressure drying preparation method and application thereof 中南大学 2020-01-31 CN disclosed
US-10022471-B2 Calcium phosphate cements and methods for using the same SKELETAL KINETICS, LLC (US) 2018-07-17 US disclosed
US-9827346-B2 Rapid setting high strength calcium phosphate cements comprising cyclodextrins SKELETAL KINETICS, LLC (US) 2017-11-28 US disclosed
EP-1771184-B1 CALCIUM PHOSPHATE CEMENTS AND METHODS FOR USING THE SAME SKELETAL KINETICS LLC (US) 2016-07-13 EP disclosed
US-20160030626-A1 Rapid Setting High Strength Calcium Phosphate Cements Comprising Cyclodextrins COLSON MEDICAL, LLC 2016-02-04 US disclosed
US-9101665-B2 Rapid setting high strength calcium phosphate cements comprising cyclodextrins SKELETAL KINETICS, LLC (US) 2015-08-11 US disclosed
US-20140202359-A1 Rapid Setting High Strength Calcium Phosphate Cements Comprising Cyclodextrins SKELETAL KINETICS, LLC 2014-07-24 US disclosed
US-8771748-B2 Rapid setting calcium phosphate cements SKELETAL KINETICS, LLC (US) 2014-07-08 US disclosed
US-8673364-B2 Rapid setting high strength calcium phosphate cements comprising cyclodextrins SKELETAL KINETICS, LLC (US) 2014-03-18 US disclosed
US-20130273118-A1 Calcium Phosphate Cements and Methods for Using the Same COLSON MEDICAL, LLC 2013-10-17 US disclosed
WO-2004110316-A1 CALCIUM PHOSPHATE CEMENTS PREPARED FROM SILICATE-PHOSPHATE SOLUTIONS SKELETAL KINETICS, LLC (US) 2004-12-23 WO disclosed
US-20040250730-A1 Calcium phosphate cements prepared from silicate-phosphate solutions SKELETAL KINETICS, LLC 2004-12-16 US disclosed
CN-1542071-A Composition for forming porous film, porous film and method for forming the same, interlevel insulator film and semiconductor device ��Խ��ѧ��ҵ��ʽ���� 2004-11-03 CN disclosed
US-20040188809-A1 Composition for forming porous film, porous film and method for forming the same, interlevel insulator film and semiconductor device SHIN-ETSU CHEMICAL CO., LTD. 2004-09-30 US disclosed
US-6719993-B2 Calcium phosphate cements prepared from silicate solutions SKELETAL KINETICS, LLC 2004-04-13 US disclosed
EP-1284680-A1 CALCIUM PHOSPHATE CEMENTS PREPARED FROM SILICATE SOLUTIONS Constantz, Brent R. (US) 2003-02-26 EP disclosed
US-20020098245-A1 Calcium phosphate cements prepared from silicate solutions SKELETAL KINETICS LLC 2002-07-25 US disclosed
US-6375935-B1 Calcium phosphate cements prepared from silicate solutions SKELETAL KINETICS LLC 2002-04-23 US disclosed
WO-2001082834-A1 CALCIUM PHOSPHATE CEMENTS PREPARED FROM SILICATE SOLUTIONS CONSTANTZ BRENT R (US) 2001-11-08 WO disclosed
US-4225398-A Method of improving the corrosion resistance of an anodically oxidized surface film on aluminum articles YOSHIDA KOGYO K.K. (JP) 1980-09-30 US disclosed