Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166055 | 0.90 | NOTUM (0.35) | — | |
| SCHEMBL25166146 | 0.80 | PARP1 (0.37) | PARP1 | |
| SCHEMBL25166010 | 0.79 | PARP1 (0.42) | PARP1 | |
| SCHEMBL25166256 | 0.78 | MAPT (0.37) | — | |
| SCHEMBL30329748 | 0.72 | GPR35 (0.37) | PARP1 | |
| SCHEMBL30695888 | 0.72 | PARP1 (0.39) | PARP1 | |
| SCHEMBL4107808 | 0.72 | PARP1 (0.39) | PARP1 | |
| SCHEMBL4100100 | 0.72 | PARP1 (0.39) | PARP1 | |
| SCHEMBL30768351 | 0.72 | PARP1 (0.39) | PARP1 | |
| SCHEMBL24373459 | 0.71 | NOTUM (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647610-A | Novel modulators of EHMT1 and EHMT2 and therapeutic uses thereof | 探戈医药股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| EP-4416143-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | Tango Therapeutics, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |