Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 14/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13038833 | 0.95 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL12391938 | 0.95 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL15961701 | 0.83 | CTSK (0.61) | CTSKCTSS | |
| SCHEMBL31059571 | 0.83 | TDP1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL12734600 | 0.83 | CTSK (0.61) | CTSKCTSS | |
| SCHEMBL24687980 | 0.83 | TDP1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL361540 | 0.83 | TDP1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL12734596 | 0.83 | CTSK (0.61) | CTSKCTSS | |
| SCHEMBL30803360 | 0.83 | CA1 (0.43) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL29775534 | 0.83 | CA1 (0.43) | CA1CA2CA7CTSKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |