Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31108011 | 1.00 | ADRA2A (0.33) | ADRA2AAKR1B1ADRA2BADRA2CADRA1A | |
| SCHEMBL25166675 | 0.80 | MAP3K14 (0.45) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL12828516 | 0.79 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL14197670 | 0.79 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL13498384 | 0.79 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL25659973 | 0.76 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL25166247 | 0.73 | — | — | |
| SCHEMBL16509739 | 0.72 | KDM4E (0.40) | ADRA2AADRA2BADRA1A | |
| SCHEMBL16509702 | 0.72 | KDM4E (0.40) | ADRA2AADRA2BADRA1A | |
| SCHEMBL8135027 | 0.72 | ADRA2A (0.33) | ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |