SCHEMBL25166152

SCHEMBL25166152

CC1=CCN(C)[C@@H](C(F)F)CC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25166151 1.00 LMNA (0.31) LMNA
SCHEMBL25166120 1.00 LMNA (0.31) LMNA
SCHEMBL25166013 0.72 LMNA (0.34) LMNA
SCHEMBL25165982 0.72 LMNA (0.34) LMNA
SCHEMBL25165980 0.72 LMNA (0.34) LMNA
SCHEMBL25166277 0.70 LMNA (0.31) LMNA
SCHEMBL25166541 0.70 LMNA (0.31) LMNA
SCHEMBL25166637 0.70 LMNA (0.31) LMNA
SCHEMBL25166160 0.67 LMNA (0.34) LMNA
SCHEMBL25166148 0.67 LMNA (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064586-A1 NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF TANGO THERAPEUTICS, INC. (US) 2023-04-20 WO disclosed