Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166010 | 0.79 | PARP1 (0.42) | PARP1PRKCICYP2A6 | |
| SCHEMBL6637296 | 0.72 | PARP1 (0.59) | PARP1PRKCI | |
| SCHEMBL29661355 | 0.72 | PARP1 (0.59) | PARP1PRKCI | |
| SCHEMBL25166593 | 0.69 | PARP1 (0.34) | PARP1 | |
| SCHEMBL1976575 | 0.68 | PARP1 (0.46) | PARP1PRKCI | |
| SCHEMBL31107976 | 0.66 | PARP1 (0.33) | PARP1 | |
| SCHEMBL25166146 | 0.66 | PARP1 (0.37) | PARP1CYP2A6 | |
| SCHEMBL13705933 | 0.64 | PARP1 (0.36) | PARP1CYP2A6 | |
| SCHEMBL23363798 | 0.64 | GAA (0.33) | PARP1 | |
| SCHEMBL25166014 | 0.64 | PARP1 (0.36) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |