Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166167 | 0.82 | USP2 (0.30) | USP2 | |
| SCHEMBL14343552 | 0.82 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL25166098 | 0.80 | — | — | |
| SCHEMBL25166598 | 0.80 | — | — | |
| SCHEMBL25166348 | 0.79 | — | — | |
| SCHEMBL6593765 | 0.74 | ITGA4 (0.44) | — | |
| SCHEMBL6593761 | 0.74 | ITGA4 (0.44) | — | |
| SCHEMBL7293819 | 0.74 | ITGA4 (0.44) | — | |
| SCHEMBL25166308 | 0.74 | — | — | |
| SCHEMBL19972867 | 0.72 | KMT2A (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |