Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329952 | 1.00 | EHMT2 (0.34) | EHMT2EHMT1ALDH1A1MAPTIGF1R | |
| SCHEMBL30329859 | 0.89 | EHMT2 (0.35) | EHMT2EHMT1ALDH1A1MAPTIGF1R | |
| SCHEMBL25166183 | 0.89 | EHMT2 (0.35) | EHMT2EHMT1ALDH1A1MAPTIGF1R | |
| SCHEMBL30329841 | 0.79 | ALDH1A1 (0.38) | EHMT2EHMT1ALDH1A1MAPT | |
| SCHEMBL25166080 | 0.79 | ALDH1A1 (0.35) | EHMT2EHMT1ALDH1A1MAPTIGF1R | |
| SCHEMBL30329937 | 0.79 | ALDH1A1 (0.35) | EHMT2EHMT1ALDH1A1MAPTIGF1R | |
| SCHEMBL25166482 | 0.79 | ALDH1A1 (0.38) | EHMT2EHMT1ALDH1A1MAPT | |
| SCHEMBL30329850 | 0.78 | ALDH1A1 (0.34) | EHMT2EHMT1ALDH1A1MAPTIGF1R | |
| SCHEMBL25166027 | 0.78 | ALDH1A1 (0.34) | EHMT2EHMT1ALDH1A1MAPTIGF1R | |
| SCHEMBL25166385 | 0.77 | EHMT2 (0.53) | EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |