Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166839 | 1.00 | MAOB (0.43) | MAOBMAOAGPR35KDM4EALDH1A1 | |
| SCHEMBL25444937 | 0.88 | MAOB (0.41) | MAOBMAOAGPR35KDM4EALDH1A1 | |
| SCHEMBL25444936 | 0.88 | MAOB (0.41) | MAOBMAOAGPR35KDM4EALDH1A1 | |
| SCHEMBL25443678 | 0.78 | GPR35 (0.39) | MAOBMAOAGPR35KDM4EALDH1A1 | |
| SCHEMBL737629 | 0.76 | GPR35 (0.66) | MAOBMAOAGPR35ALDH1A1HSD17B10 | |
| SCHEMBL29406299 | 0.76 | GPR35 (0.66) | MAOBMAOAGPR35ALDH1A1HSD17B10 | |
| SCHEMBL23155088 | 0.75 | MAOB (0.54) | MAOBMAOAGPR35KDM4EALDH1A1 | |
| SCHEMBL25167980 | 0.75 | MAOB (0.58) | MAOBMAOAKDM4EALDH1A1MAPT | |
| SCHEMBL25443886 | 0.74 | GPR35 (0.44) | MAOBMAOAGPR35KDM4EHSD17B10 | |
| SCHEMBL25444789 | 0.73 | GPR35 (0.47) | MAOBMAOAGPR35HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |
| WO-2023077162-A2 | METHODS TO QUANTIFY AFFINITY AND SELECTIVITY OF COMPOUNDS FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION (US) | 2023-05-04 | — | — | WO | disclosed |