SCHEMBL2517022

SCHEMBL2517022

C=C(C)C(=O)OCC(CC)NC

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.43
ALDH1A1 P00352 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.32
GAA P10253 2/20 0.32
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26031177 0.85 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL28343507 0.84 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL2520781 0.82 THRB (0.49) TSHRTHRBALDH1A1
SCHEMBL4979118 0.81 TSHR (0.50) TSHRTHRBALDH1A1SMN1; SMN2CYP1A2
SCHEMBL22717165 0.81 TSHR (0.50) TSHRTHRBALDH1A1SMN1; SMN2ALOX15
SCHEMBL26032044 0.81 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL29044527 0.80 TSHR (0.54) TSHRTHRB
SCHEMBL27398964 0.79 TSHR (0.61) TSHRTHRBALDH1A1GAAMGAM
SCHEMBL150581 0.79 TSHR (0.61) TSHRTHRBALDH1A1GAAMGAM
SCHEMBL17345216 0.78 TSHR (0.47) TSHRTHRBALDH1A1SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5760136-A FORMING AN ADDITION-CONDENSATION COPOLYMER BY POLYMERIZING AN AZO-CONTAINING POLYSILOXANE AND AN UNSATURATED MONOMER; CATIONIC AND NONIONIC POLYMERS; POLYAMPHOLYTES; COATINGS; ADHESIVES; PAINTS; HAIR COSMETICS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-02 US claimed
US-20250224314-A1 DEVICE FOR TISSUE SECTION IMMOBILIZATION AND RETENTION Singular Genomics Systems, Inc. 2025-07-10 US disclosed
US-12298211-B2 Device for tissue section immobilization and retention Singular Genomics Systems, Inc. (US) 2025-05-13 US disclosed
US-20250067638-A1 DEVICE FOR TISSUE SECTION IMMOBILIZATION AND RETENTION FIRST-CITIZENS BANK & TRUST COMPANY 2025-02-27 US disclosed
US-20250067639-A1 METHOD FOR TISSUE SECTION IMMOBILIZATION AND RETENTION FIRST-CITIZENS BANK & TRUST COMPANY 2025-02-27 US disclosed
US-20250034623-A1 MANIPULATING AND DETECTING BIOLOGICAL SAMPLES FIRST-CITIZENS BANK & TRUST COMPANY 2025-01-30 US disclosed
US-12181388-B2 Device for tissue section immobilization and retention Singular Genomics Systems, Inc. (US) 2024-12-31 US disclosed
US-12158402-B2 Manipulating and detecting biological samples Singular Genomics Systems, Inc. (US) 2024-12-03 US disclosed
EP-4423664-A1 MANIPULATING AND DETECTING BIOLOGICAL SAMPLES Singular Genomics Systems, Inc. (US) 2024-09-04 EP disclosed
US-20240280446-A1 DEVICE FOR TISSUE SECTION IMMOBILIZATION AND RETENTION FIRST-CITIZENS BANK & TRUST COMPANY 2024-08-22 US disclosed
WO-2023076832-A1 MANIPULATING AND DETECTING BIOLOGICAL SAMPLES Singular Genomics Systems, Inc. (US) 2023-05-04 WO disclosed
US-20110250511-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-10-13 US disclosed
US-7700129-B2 Polymer actuator SONY CORPORATION (JP) 2010-04-20 US disclosed
US-20080057434-A1 METHOD OF PRODUCING NON-MAGNETIC ONE-COMPONENT TONER FOR DEVELOPING ELECTROSTATIC IMAGE ZEON CORPORATION (JP) 2008-03-06 US disclosed
US-20070196492-A1 Stimuli-Responesive Hydrogel,Production Method Of Stimuli-Responsive Hydrogel,And Polymer Actuator Using Stimuli-Responsive Hydrogel SONY CORPORATION (JP) 2007-08-23 US disclosed
US-20070190150-A1 Polymer actuator SONY CORPORATION (JP) 2007-08-16 US disclosed
EP-1739821-A1 POLYMER ACTUATOR Sony Corporation (JP) 2007-01-03 EP disclosed
EP-0779318-B1 Silicon-containing block copolymer WAKO PURE CHEMICAL INDUSTIES L (JP) 2000-02-16 EP disclosed
US-5760136-A FORMING AN ADDITION-CONDENSATION COPOLYMER BY POLYMERIZING AN AZO-CONTAINING POLYSILOXANE AND AN UNSATURATED MONOMER; CATIONIC AND NONIONIC POLYMERS; POLYAMPHOLYTES; COATINGS; ADHESIVES; PAINTS; HAIR COSMETICS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-02 US disclosed
EP-0779318-A1 Silicon-containing block copolymer Wako Pure Chemical Industries, Ltd. (JP) 1997-06-18 EP disclosed