Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688633 | 0.81 | KMO (0.43) | KMOKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL18179501 | 0.78 | KMO (0.42) | KMOKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL16794080 | 0.78 | KMO (0.42) | KMOKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL18179480 | 0.78 | KMO (0.45) | KMOKDM4EALDH1A1POLBMAPT | |
| SCHEMBL17744653 | 0.78 | KMO (0.51) | KMOKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31375122 | 0.77 | KMO (0.61) | KMOKDM4EALDH1A1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL29676742 | 0.77 | KMO (0.41) | KMOKDM4EALDH1A1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL18170402 | 0.77 | KMO (0.41) | KMOKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL21508293 | 0.76 | AAK1 (0.42) | KMOAAK1 | |
| SCHEMBL444442 | 0.75 | KMT2A (0.56) | KMOKDM4EALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023080732-A1 | COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF | 주식회사 유빅스테라퓨틱스 | 2023-05-11 | — | — | WO | disclosed |