SCHEMBL2517211

SCHEMBL2517211

CCCCCCC(O)CCCCCCCCCCC(=O)NC(CC)[N+](C)(C)[O-]

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.58
FFAR4 Q5NUL3 1/20 0.50
FFAR1 O14842 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GPR84 Q9NQS5 2/20 0.48
MAPK1 P28482 1/20 0.47
CPT2 P23786 1/20 0.46
CPT1A P50416 1/20 0.46
CPT1B Q92523 1/20 0.46
NFKB1 P19838 1/20 0.45
NOD1 Q9Y239 1/20 0.43
PLA2G2C Q5R387 1/20 0.43
DNM1 Q05193 1/20 0.43
PLA2G4A P47712 2/20 0.42
PLA2G10 O15496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL335873 0.91 FAAH (0.56) FAAHMEN1KMT2AMAPK1CPT2
SCHEMBL249653 0.91 FAAH (0.56) FAAHMEN1KMT2AMAPK1CPT2
SCHEMBL2515616 0.91 FAAH (0.56) FAAHMEN1KMT2AMAPK1CPT2
SCHEMBL27600 0.91 FAAH (0.56) FAAHMEN1KMT2AMAPK1CPT2
SCHEMBL2523709 0.91 FAAH (0.56) FAAHMEN1KMT2AMAPK1CPT2
SCHEMBL2521250 0.91 FAAH (0.56) FAAHMEN1KMT2AMAPK1CPT2
SCHEMBL9064003 0.84 KMT2A (0.44) FAAHMEN1KMT2AMAPK1CPT2
SCHEMBL27553836 0.83 FAAH (0.52) FAAHMEN1KMT2A
SCHEMBL8993770 0.83 FAAH (0.52) FAAHMEN1KMT2A
SCHEMBL2514525 0.83 FAAH (0.52) FAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137820-B Cosmetic composition, cosmetic and external preparation for skin 陶氏东丽株式会社 2022-05-27 CN disclosed
CN-110996900-A Skin film forming agent for cosmetic and cosmetic containing same 陶氏东丽株式会社 2020-04-10 CN disclosed
EP-2022812-B1 POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION DOW CORNING TORAY CO LTD (JP) 2014-04-23 EP disclosed
US-8034891-B2 Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, their production methods, and cosmetic preparation DOW CORNING TORAY COMPANY, LTD. (JP) 2011-10-11 US disclosed
US-20100036062-A1 Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation DOW TORAY CO., LTD. (JP) 2010-02-11 US disclosed
EP-2022812-A1 POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION Dow Corning Toray Co., Ltd. (JP) 2009-02-11 EP disclosed