SCHEMBL25172149

SCHEMBL25172149

C[C@H](N)Cc1ccc2ccoc2c1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 6/20 0.67
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54
HTR2B P41595 1/20 0.54
PNMT P11086 1/20 0.47
TAAR1 Q96RJ0 2/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31079721 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL29366170 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL5987271 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL31079904 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
Hydrochloric Acid SCHEMBL5987162 0.98 HTR1B (0.65) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL5988009 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL29528156 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL24429342 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL25237253 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL13034824 0.86 HTR1B (0.71) HTR1BHTR2AHTR2CHTR2BCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444283-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-10-16 EP claimed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO claimed
EP-4727538-A2 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2026-04-22 EP disclosed
WO-2024259343-A2 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2024-12-19 WO disclosed
EP-4444283-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-10-16 EP disclosed
EP-4426291-A1 INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-09-11 EP disclosed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO disclosed
WO-2023081306-A1 INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-05-11 WO disclosed