SCHEMBL29366170

SCHEMBL29366170

CC(N)Cc1ccc2ccoc2c1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 6/20 0.67
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54
HTR2B P41595 1/20 0.54
PNMT P11086 1/20 0.47
TAAR1 Q96RJ0 2/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25172149 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL31079721 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL5987271 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL31079904 1.00 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
Hydrochloric Acid SCHEMBL5987162 0.98 HTR1B (0.65) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL5988009 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL29528156 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL24429342 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL25237253 0.86 HTR1B (0.67) HTR1BHTR2AHTR2CHTR2BPNMT
SCHEMBL13034824 0.86 HTR1B (0.71) HTR1BHTR2AHTR2CHTR2BCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727538-A2 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2026-04-22 EP claimed
EP-4704826-A1 COMPOSITIONS AND METHODS FOR TREATING POST-TRAUMATIC STRESS DISORDER Yale University (US) 2026-03-11 EP claimed
EP-4673125-A1 R-MDMA FOR TREATMENT OF PAIN Mind Medicine, Inc. (US) 2026-01-07 EP claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
EP-4615585-A1 METHODS OF USING TRAZODONE TO REVERSE THE EFFECTS OF 5-HT2A RECEPTOR AGONISTS Gilgamesh Pharmaceuticals, Inc. (US) 2025-09-17 EP claimed
US-20240423950-A1 5-MAPB OR 6-APB FOR USE IN DRUG-ASSISTED PSYCHOTHERAPY Clearmind Medicine Inc. (IL) 2024-12-26 US claimed
WO-2024259343-A2 NEW FORMULATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2024-12-19 WO claimed
WO-2024226995-A1 COMPOSITIONS AND METHODS FOR TREATING POST-TRAUMATIC STRESS DISORDER YALE UNIVERSITY (US) 2024-10-31 WO claimed
EP-4444283-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-10-16 EP claimed
US-20230233688-A1 MDMA PRODRUGS TO ASSIST PSYCHOTHERAPY Mind Medicine, Inc. (US) 2023-07-27 US claimed
US-20230218570-A1 Methods and Compositions for Treating Mild Traumatic Brain Injury, Post-Traumatic Stress Disorder and Mild Traumatic Brain Injury with Post Traumatic Stress Disorder LOBE SCIENCES LTD. (CA) 2023-07-13 US claimed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO claimed
WO-2023057953-A1 5-MAPB OR 6-APB FOR USE IN DRUG-ASSISTED PSYCHOTHERAPY Clearmind Medicine Inc. (IL) 2023-04-13 WO claimed
US-20230066171-A1 SYNTHESIS ROUTES TO ACCESS MDMA PRODRUGS BY USING CONTROLLED AND NON-CONTROLLED INTERMEDIATES Mind Medicine, Inc. (US) 2023-03-02 US claimed
WO-2023028022-A1 SYNTHESIS ROUTES TO ACCESS MDMA PRODRUGS BY USING CONTROLLED AND NON-CONTROLLED INTERMEDIATES Mind Medicine, Inc. (US) 2023-03-02 WO claimed
WO-2023283386-A2 SAFER PSYCHOACTIVE COMPOSITIONS ARCADIA MEDICINE, INC. (US) 2023-01-12 WO claimed
WO-2022256720-A2 ENANTIOMERIC ENTACTOGEN COMPOSITIONS AND METHODS OF THEIR USE ARCADIA MEDICINE, INC. (US) 2022-12-08 WO claimed
WO-2022106947-A1 MDMA PRODRUGS TO ASSIST PSYCHOTHERAPY LIECHTI MATTHIAS EMANUEL (CH) 2022-05-27 WO claimed
US-20220151986-A1 MDMA PRODRUGS TO ASSIST PSYCHOTHERAPY Mind Medicine, Inc. (US) 2022-05-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A HTR1B 10/4885HTR2A 14/4885HTR2C 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.