Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | TTK | P33981 | 4/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386133 | 0.97 | SYK (0.39) | SYKPTK6PTK2TTKMAPKAPK5 | |
| Hydrochloric Acid SCHEMBL30386327 | 0.94 | SYK (0.38) | SYKPTK6PTK2TTKMAPKAPK5 | |
| SCHEMBL25170422 | 0.93 | SYK (0.41) | SYKPTK6TTKMAPKAPK5IDO1 | |
| Hydrochloric Acid SCHEMBL30385672 | 0.92 | SYK (0.40) | SYKPTK6TTKMAPKAPK5IDO1 | |
| SCHEMBL30171749 | 0.92 | SYK (0.49) | SYKPTK6MAPKAPK5AURKB | |
| SCHEMBL30385514 | 0.92 | SYK (0.40) | SYKPTK6TTKMAPKAPK5IDO1 | |
| SCHEMBL30171980 | 0.92 | TTK (0.41) | SYKPTK6PTK2TTKIDO1 | |
| SCHEMBL22123172 | 0.92 | TTK (0.41) | SYKPTK6PTK2TTKIDO1 | |
| SCHEMBL22124340 | 0.91 | CDK2 (0.44) | SYKPTK6TTKMAPKAPK5IDO1 | |
| SCHEMBL30386051 | 0.91 | PTK6 (0.40) | SYKPTK6PTK2TTKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2026-02-18 | — | — | EP | disclosed |
| US-20230141600-A1 | IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230141600-A1 | IMIDAZOPYRAZINE DERIVATIVES | IKZF3, RRP15, IK | SYK 256/4885PTK6 925/4885PTK2 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.