Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.38 |
| ▸ | TTK | P33981 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170422 | 0.97 | SYK (0.41) | SYKPTK6TTKDHODHMEN1 | |
| SCHEMBL25173403 | 0.97 | SYK (0.41) | SYKPTK6TTKPTK2MAPKAPK5 | |
| SCHEMBL30385514 | 0.96 | SYK (0.40) | SYKPTK6TTKDHODHMEN1 | |
| Hydrochloric Acid SCHEMBL30385672 | 0.96 | SYK (0.40) | SYKPTK6TTKDHODHMEN1 | |
| Hydrochloric Acid SCHEMBL30386327 | 0.91 | SYK (0.38) | SYKPTK6TTKPTK2MAPKAPK5 | |
| SCHEMBL30171749 | 0.89 | SYK (0.49) | SYKPTK6MAPKAPK5 | |
| SCHEMBL30385532 | 0.89 | PTK6 (0.37) | SYKPTK6TTKDHODHPTK2 | |
| SCHEMBL22123172 | 0.89 | TTK (0.41) | SYKPTK6TTKPTK2IDO1 | |
| SCHEMBL30171980 | 0.89 | TTK (0.41) | SYKPTK6TTKPTK2IDO1 | |
| SCHEMBL22124340 | 0.88 | CDK2 (0.44) | SYKPTK6TTKMAPKAPK5IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |