Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25176651 | 1.00 | TSHR (0.52) | TSHRLMNATP53ALOX15HTT | |
| SCHEMBL25176202 | 1.00 | TSHR (0.52) | TSHRLMNATP53ALOX15HTT | |
| SCHEMBL25173767 | 0.93 | HIF1A (0.56) | TSHRLMNATP53ALOX15HTT | |
| SCHEMBL25173725 | 0.93 | HIF1A (0.56) | TSHRLMNATP53ALOX15HTT | |
| SCHEMBL25170511 | 0.84 | ADORA3 (0.47) | TSHRTP53RXFP1HIF1AADORA3 | |
| SCHEMBL25173663 | 0.84 | ADORA3 (0.47) | TSHRTP53RXFP1HIF1AADORA3 | |
| SCHEMBL25170603 | 0.83 | TP53 (0.75) | TSHRLMNATP53ALOX15HTT | |
| SCHEMBL25173544 | 0.83 | TP53 (0.75) | TSHRLMNATP53ALOX15HTT | |
| SCHEMBL25170460 | 0.83 | TP53 (0.75) | TSHRLMNATP53ALOX15HTT | |
| SCHEMBL25176615 | 0.83 | TP53 (0.75) | TSHRLMNATP53ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472642-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023078482-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-05-11 | — | — | WO | disclosed |