Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.48 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30171640 | 0.97 | TTK (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL22124284 | 0.97 | TTK (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL22139112 | 0.88 | TTK (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL24910493 | 0.88 | TTK (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL30171555 | 0.88 | TTK (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL22123500 | 0.84 | MAPKAPK5 (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL24870705 | 0.84 | TTK (0.48) | TTKMAPKAPK5 | |
| SCHEMBL30172021 | 0.84 | TTK (0.48) | TTKMAPKAPK5 | |
| SCHEMBL22142950 | 0.84 | MAPKAPK5 (0.47) | TTKMAPKAPK5AXL | |
| SCHEMBL30171796 | 0.84 | MAPKAPK5 (0.47) | TTKMAPKAPK5AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |