SCHEMBL25175403

SCHEMBL25175403

O=C(O)CC1CCN(c2c(F)cc([N+](=O)[O-])cc2F)CC1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28995471 0.87 FFAR4 (0.53) FFAR4
SCHEMBL19510979 0.85 MAPT (0.45) FFAR4
SCHEMBL29179883 0.85 ALDH1A1 (0.39) FFAR4
SCHEMBL25169812 0.83 MAPT (0.48) FFAR4
SCHEMBL27098839 0.83 CSF1R (0.40) FFAR4
SCHEMBL25172775 0.82 FFAR4 (0.45) FFAR4
SCHEMBL30376848 0.80 FFAR4 (0.48) FFAR4
SCHEMBL23582916 0.78 FFAR4 (0.54) FFAR4
SCHEMBL19510602 0.78 FFAR4 (0.46) FFAR4
SCHEMBL19665039 0.78 FFAR4 (0.46) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559492-B2 BRAF degraders C4 THERAPEUTICS, INC. (US) 2026-02-24 — — US disclosed
US-20230145336-A1 BRAF DEGRADERS C4 THERAPEUTICS, INC. (US) 2023-05-11 — — US disclosed
US-20230145336-A1 BRAF DEGRADERS C4 THERAPEUTICS, INC. (US) 2023-05-11 — — US disclosed
EP-4168407-A1 BRAF DEGRADERS C4 Therapeutics, Inc. (US) 2023-04-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559492-B2 BRAF degraders BRAF, NRAS, HRAS FFAR4 1147/4885
US-20230145336-A1 BRAF DEGRADERS BRAF, NRAS, RAF1 FFAR4 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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