Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112514 | 0.97 | PTK2 (0.37) | PTK2BTKPTK6TTK | |
| Formic Acid SCHEMBL25173464 | 0.94 | PTK2 (0.34) | PTK2PTK6TTK | |
| SCHEMBL24112441 | 0.91 | PTK2 (0.36) | PTK2PTK6TTK | |
| Formic Acid SCHEMBL25173598 | 0.91 | PTK2 (0.32) | PTK2PTK6TTK | |
| Hydrochloric Acid SCHEMBL25170324 | 0.89 | PTK2 (0.42) | PTK2PTK6TTK | |
| SCHEMBL24112362 | 0.88 | PTK2 (0.34) | PTK2PTK6TTK | |
| Formic Acid SCHEMBL30385574 | 0.88 | PTK6 (0.33) | PTK2PTK6TTK | |
| Formic Acid SCHEMBL25176064 | 0.87 | PTK6 (0.32) | PTK6TTK | |
| Iodide SCHEMBL25170265 | 0.87 | TTK (0.33) | PTK2BTKPTK6TTK | |
| Iodide SCHEMBL25170263 | 0.87 | TTK (0.33) | PTK2BTKPTK6TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230141600-A1 | IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230141600-A1 | IMIDAZOPYRAZINE DERIVATIVES | IKZF3, RRP15, IK | PTK2 3799/4885BTK 239/4885PTK6 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.