SCHEMBL251775

SCHEMBL251775

C[Si](C)(C)OO[Si](O)(O)OCCc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
AKR1B10 O60218 1/20 0.38
AKR1B1 P15121 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TSHR P16473 1/20 0.37
HDAC3 O15379 1/20 0.36
MAPK1 P28482 1/20 0.36
ADRA1A P35348 1/20 0.36
HDAC4 P56524 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28784420 0.82
SCHEMBL9911294 0.81 SMN1; SMN2 (0.44) IDO1HCAR2SMN1; SMN2AKR1B10AKR1B1
SCHEMBL28677549 0.80 HCAR2 (0.36) IDO1HCAR2SMN1; SMN2AKR1B10AKR1B1
SCHEMBL9621399 0.77 IDO1 (0.45) IDO1HCAR2LMNASMN1; SMN2CA1
SCHEMBL4237137 0.77 TDP1 (0.46) IDO1HCAR2LMNASMN1; SMN2TDP1
SCHEMBL766905 0.77 SMN1; SMN2 (0.44) IDO1SMN1; SMN2TDP1CA1CA2
SCHEMBL21046342 0.76 IDO1 (0.42) IDO1LMNASMN1; SMN2HDAC3MAPK1
SCHEMBL28226710 0.75 IDO1 (0.48) IDO1LMNASMN1; SMN2TDP1HDAC3
SCHEMBL10044994 0.73 IDO1 (0.55) IDO1LMNAADRA1ASLC6A3
SCHEMBL3036323 0.72 CA1 (0.47) IDO1HCAR2SMN1; SMN2TDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2613 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380541-A1 PERSONAL CARE COMPOSITIONS BASED ON AMINOACIDS AND SKIN PENETRATION ENHANCER Colgate-Palmolive Company (US) 2024-06-12 EP claimed
CN-117956970-A Personal care compositions based on amino acids and skin penetration enhancers 高露洁-棕榄公司 2024-04-30 CN claimed
CN-116546962-A Skin care composition 莱雅公司 2023-08-04 CN claimed
US-20230181437-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2023-06-15 US claimed
WO-2023039220-A1 PERSONAL CARE COMPOSITIONS BASED ON AMINOACIDS AND SKIN PENETRATION ENHANCER COLGATE-PALMOLIVE COMPANY (US) 2023-03-16 WO claimed
CN-115315246-A Solid composition in the form of a water-in-oil emulsion 莱雅公司 2022-11-08 CN claimed
US-11389381-B2 Cosmetic solid composition comprising a non volatile hydrocarbonated oil, waxes and a high content from non volatile phenylated silicone oil L'OREAL (FR) 2022-07-19 US claimed
WO-2022110175-A1 COMPOSITIONS FOR SKIN CARE L'OREAL (FR) 2022-06-02 WO claimed
EP-3883653-A1 COSMETIC MAKE-UP COMPOSITION WITH LONG-LASTING SKIN-PERFECTING EFFECT L V M H RECHERCHE (FR) 2021-09-29 EP claimed
WO-2021120084-A1 SOLID COMPOSITION IN THE FORM OF WATER-IN-OIL EMULSION L'OREAL (FR) 2021-06-24 WO claimed
EP-1184028-A1 Non-transfer cosmetic composition comprising a non-volatile silicone, a non-volatile hydrocarbon oil and an inert particulate phase L'OREAL (FR) 2002-03-06 EP claimed
EP-1064930-B1 Care or make-up composition containing fibers and a hydrophilic organopolysiloxane OREAL (FR) 2002-02-06 EP claimed
US-20010031269-A1 Transfer-resistant cosmetic composition comprising a non-volatile silicone compound and a non-volatile hydrocarbon-based oil which is incompatible with this silicone compound L'OREAL (FR) 2001-10-18 US claimed
EP-0891767-B1 Glossy composition containing aromatic oils thickened with an alkylether of a polysaccharide OREAL (FR) 2001-07-18 EP claimed
EP-1112734-A2 Non-transfer cosmetic composition comprising a non-volatile silicon compound, and a non-volatile hydrocarbon oil incompatible with the silicone compound L'OREAL (FR) 2001-07-04 EP claimed
EP-1064930-A1 Care or make-up composition containing fibers and a hydrophilic organopolysiloxane L'OREAL (FR) 2001-01-03 EP claimed
EP-1053742-A1 Anhydrous skin care or make-up compositions containing fibres and polyols L'OREAL (FR) 2000-11-22 EP claimed
EP-1008339-A1 Cosmetic composition containing an association of acexamic acid and polyols L'OREAL (FR) 2000-06-14 EP claimed
US-5961998-A Glossy composition containing aromatic oils thickened by a polysaccharide ether L'OREAL (FR) 1999-10-05 US claimed
EP-0891767-A1 Glossy composition containing aromatic oils thickened with an alkylether of a polysaccharide L'OREAL (FR) 1999-01-20 EP claimed