SCHEMBL25178155

SCHEMBL25178155

C=CC(CCCC)CCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.46
TSHR P16473 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39
CA2 P00918 1/20 0.39
OPRM1 P35372 1/20 0.39
FDPS P14324 3/20 0.37
GPR84 Q9NQS5 2/20 0.37
SPHK1 Q9NYA1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9015831 1.00 DNM1 (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL10899262 1.00 DNM1 (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL25171286 1.00 DNM1 (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL9015991 1.00 DNM1 (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL25181794 0.97 TSHR (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL25171279 0.97 TSHR (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL25181774 0.97 TSHR (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL9015898 0.97 TSHR (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL10921449 0.97 TSHR (0.46) DNM1TSHRSMN1; SMN2LMNATHRB
SCHEMBL25172438 0.97 TSHR (0.46) DNM1TSHRSMN1; SMN2LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed