Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30510266 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL25182256 | 0.90 | PLA2G1B (0.39) | PLA2G1BHTTL3MBTL1ATG4B | |
| SCHEMBL30510319 | 0.90 | PLA2G1B (0.39) | PLA2G1BHTTL3MBTL1ATG4B | |
| SCHEMBL25173040 | 0.89 | PRSS1 (0.39) | ALDH1A1KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL30510294 | 0.89 | PPARG (0.41) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL25178770 | 0.89 | PPARG (0.41) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL30510305 | 0.88 | MEN1 (0.38) | KMT2AMEN1MAPTKDM4E | |
| SCHEMBL25178572 | 0.88 | MEN1 (0.38) | KMT2AMEN1MAPTKDM4E | |
| SCHEMBL25186430 | 0.88 | TSHR (0.38) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL30510341 | 0.88 | TSHR (0.38) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | KRAS, NRAS, HRAS | ALDH1A1 4838/4885KMT2A 3145/4885MEN1 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.