SCHEMBL25180

SCHEMBL25180

CCC(C)NC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13074302 1.00
Alcohol SCHEMBL11633354 0.84 ADH1B (0.42)
SCHEMBL22692614 0.79 ADH1B (0.47)
SCHEMBL28057534 0.79
SCHEMBL28234932 0.79 ADH1B (0.53)
SCHEMBL271757 0.78
SCHEMBL16232884 0.76 ADH1B (0.44)
SCHEMBL14946732 0.75 TSHR (0.38)
SCHEMBL8763373 0.74 ADH1B (0.71)
SCHEMBL9075732 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2151 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11396502-B2 Substituted heterocyclic derivatives as PI3K inhibitors INCYTE CORPORATION (US) 2022-07-26 US claimed
WO-2020102216-A1 SUBSTITUTED HETEROCYCLIC DERIVATIVES AS PI3K INHIBITORS INCYTE CORPORATION (US) 2020-05-22 WO claimed
CN-111170988-A Pyrazole formamide derivative containing substituted sulfimide acyl aryl, and preparation method and application thereof 南开大学 2020-05-19 CN claimed
US-20200148667-A1 SUBSTITUTED HETEROCYCLIC DERIVATIVES AS PI3K INHIBITORS INCYTE CORPORATION 2020-05-14 US claimed
EP-2187884-B1 ISOTHIAZOLOPYRIDINONES USEFUL FOR THE TREATMENT OF (INTER ALIA) CYSTIC FIBROSIS VERTEX PHARMA (US) 2016-03-30 EP claimed
US-20150315186-A2 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMACEUTICALS INCORPORATED 2015-11-05 US claimed
US-9134329-B2 Compositions and methods for drug-sensitization or inhibition of a cancer cell THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-09-15 US claimed
EP-1906945-B1 HCV INHIBITORS VIROBAY INC (US) 2015-08-05 EP claimed
US-20150065487-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMA (US) 2015-03-05 US claimed
US-20150031722-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMACEUTICALS INCORPORATED 2015-01-29 US claimed
WO-2000062778-A1 CYCLIC PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB CO. (US) 2000-10-26 WO claimed
US-5976756-A EXPOSURE TO LIGHT A COLOR DIFFUSION TRANSFER SILVER HALIDE EMULSION FUJI PHOTO FILM, CO., LTD. (JP) 1999-11-02 US claimed
EP-0560267-B1 Isosteric antiherpes peptide derivatives BOEHRINGER INGELHEIM CA LTD (CA) 1998-08-19 EP claimed
EP-0560274-B1 Antiherpes peptide derivatives having a ureido N-terminus BOEHRINGER INGELHEIM CA LTD (CA) 1998-06-24 EP claimed
EP-0767671-A1 METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1997-04-16 EP claimed
US-5574015-A Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1996-11-12 US claimed
WO-1994025046-A1 METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-11-10 WO claimed
WO-1993018056-A1 ISOSTERIC ANTIHERPES PEPTIDE DERIVATIVES BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-16 WO claimed
EP-0560274-A1 Antiherpes peptide derivatives having a ureido N-terminus BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP claimed
EP-0560267-A1 Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP claimed