SCHEMBL251843

SCHEMBL251843

C=C(C)Cc1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.56
HSPA5 P11021 1/20 0.52
TSHR P16473 2/20 0.46
CYP2D6 P10635 1/20 0.46
HIF1A Q16665 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45
CA12 O43570 6/20 0.43
CA2 P00918 6/20 0.43
IDO1 P14902 2/20 0.43
CA9 Q16790 5/20 0.42
MPO P05164 1/20 0.42
KEAP1 Q14145 1/20 0.42
HTR1A P08908 1/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015464 0.85 MEN1 (0.40) AKR1B1HSPA5TSHRCYP2D6HIF1A
SCHEMBL8389267 0.83 IAPP (0.52) AKR1B1HSPA5TAAR1CA2KDM4E
SCHEMBL7497072 0.81 AKR1B1 (0.60) AKR1B1HSPA5TSHRCYP2D6HIF1A
SCHEMBL6368751 0.81 AKR1B1 (0.60) AKR1B1HSPA5TSHRCYP2D6HIF1A
SCHEMBL10707835 0.81 IAPP (0.38) AKR1B1HSPA5TSHRCYP2D6HIF1A
SCHEMBL11061615 0.79 GABRA1 (0.52) AKR1B1HSPA5TAAR1CA2IDO1
SCHEMBL7735450 0.79 AKR1B1 (0.58) AKR1B1HSPA5TSHRCYP2D6HIF1A
SCHEMBL13689908 0.78 AKR1B1 (0.57) AKR1B1KDM4EMAPT
SCHEMBL5380034 0.78 TAAR1 (0.52) AKR1B1HSPA5TSHRCYP2D6HIF1A
SCHEMBL10535293 0.77 AKR1B1 (0.56) AKR1B1HSPA5TSHRCYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736442-A Electrician epoxy resin active additive, composition, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-03-22 CN claimed
CN-1255454-C Preparation of high intrinsic viscosity poly(arylene ether) resins GEN ELECTRIC (US) 2006-05-10 CN claimed
CN-1468275-A Preparation of high intrinsic viscosity poly(arylene ether) resins 通用电气公司 2004-01-14 CN claimed
US-4299911-A POLYMER CONTAINING AN ETHYLENICALLY UNSATURATED DOUBLE BOND SOMAR MANUFACTURING CO., LTD. (JP) 1981-11-10 US claimed
US-4127615-A POLYIMIDE, ALKENYLPHENOL OR ETHER CIBA-GEIGY CORPORATION (US) 1978-11-28 US claimed
JP-7018032-A None JP disclosed
JP-11140424-A None JP disclosed
JP-7126203-A None JP disclosed
JP-7070243-A None JP disclosed
JP-7304831-A None JP disclosed
JP-8245506-A None JP disclosed
JP-7330831-A None JP disclosed
US-4297284-A BY THE CYCLIZATION OF ISOBUTENYL-PYROCATECHOL OR A MIXTURE WITH METHALLYLPYROCATECHOL USING A SULFONIC ACID CATALYST RHONE-POULENC AGROCHIMIE (FR) 1981-10-27 US disclosed
US-4246169-A Flammable plastics containing a flame retardant amount of polyarylphosphates and the polyarylphosphates FMC CORPORATION (US) 1981-01-20 US disclosed
US-4220513-A FOR PRINTED CIRCUITS, COATINGS, PRINTING PLATES, ADHESIVES CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
EP-0005053-A2 Flame-retardant organic phosphates, their production, and compositions containing them FMC Corporation (US) 1979-10-31 EP disclosed
US-4140769-A ANALGESICS MILES LABORATORIES, INC. (US) 1979-02-20 US disclosed
US-4131707-A POLYMALEIMIDES CIBA-GEIGY CORPORATION (US) 1978-12-26 US disclosed
US-4127615-A POLYIMIDE, ALKENYLPHENOL OR ETHER CIBA-GEIGY CORPORATION (US) 1978-11-28 US disclosed
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US disclosed