Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406677 | 1.00 | SMO (0.35) | SMOPDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL745737 | 0.90 | SMO (0.43) | SMOPDE10A | |
| SCHEMBL30408650 | 0.86 | SCN9A (0.39) | PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25188756 | 0.86 | SCN9A (0.39) | PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15180526 | 0.81 | HRH3 (0.42) | PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6267340 | 0.79 | PDE10A (0.31) | PDE10A | |
| SCHEMBL15167374 | 0.78 | PTPN11 (0.34) | PDE10A | |
| SCHEMBL745011 | 0.78 | SMN1; SMN2 (0.35) | PDE10ASMN1; SMN2 | |
| SCHEMBL7659846 | 0.77 | MAPT (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25190685 | 0.77 | KMT2A (0.33) | PDE10ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |