Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | SMO | Q99835 | 11/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25264481 | 1.00 | TRPV1 (0.47) | TRPV1SMOLIMK2BRD4SMARCA2 | |
| SCHEMBL30426401 | 0.83 | MAP4K4 (0.50) | TRPV1SMOSMARCA2SMARCA4PBRM1 | |
| SCHEMBL31105008 | 0.83 | MAP4K4 (0.50) | TRPV1SMOSMARCA2SMARCA4PBRM1 | |
| SCHEMBL30427234 | 0.79 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL25186827 | 0.77 | TRPV1 (0.47) | TRPV1SMOBRD4SMARCA2SMARCA4 | |
| SCHEMBL25264858 | 0.77 | TRPV1 (0.47) | TRPV1SMOBRD4SMARCA2SMARCA4 | |
| SCHEMBL25265269 | 0.76 | PANK3 (0.48) | SMOBRD4SMARCA2SMARCA4PBRM1 | |
| SCHEMBL25186819 | 0.76 | PANK3 (0.48) | SMOBRD4SMARCA2SMARCA4PBRM1 | |
| SCHEMBL27697487 | 0.76 | CHRM1 (0.43) | TRPV1LIMK2 | |
| SCHEMBL25267836 | 0.74 | CHRM1 (0.44) | TRPV1LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092098-A1 | HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |