Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 5/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770269 | 0.84 | GPR119 (0.47) | CHRM1CHRM2CHRM4CHRM3LIMK2 | |
| SCHEMBL4916694 | 0.84 | GPR119 (0.47) | CHRM1CHRM2CHRM4CHRM3LIMK2 | |
| SCHEMBL25267836 | 0.83 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM3LIMK2 | |
| SCHEMBL22322284 | 0.83 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM3LIMK2 | |
| SCHEMBL18145739 | 0.80 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3GRM1 | |
| SCHEMBL18149351 | 0.77 | GRM1 (0.50) | CHRM4GRM1 | |
| SCHEMBL21808506 | 0.77 | GRM1 (0.50) | CHRM4GRM1 | |
| SCHEMBL25186802 | 0.76 | TRPV1 (0.47) | LIMK2TRPV1 | |
| SCHEMBL25264481 | 0.76 | TRPV1 (0.47) | LIMK2TRPV1 | |
| SCHEMBL20135249 | 0.74 | AGTR2 (0.37) | CHRM1CHRM2CHRM4CHRM3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101080228-A | Piperazinyl-pyridine analogues | NEUROGEN CORP (US) | 2007-11-28 | — | — | CN | disclosed |