Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25264913 | 1.00 | ALDH1A1 (0.42) | ALDH1A1SLC1A3SLC1A2SLC1A1PIK3CD | |
| SCHEMBL23886210 | 0.98 | ALDH1A1 (0.43) | ALDH1A1SLC1A3SLC1A2SLC1A1PIK3CD | |
| SCHEMBL25191941 | 0.98 | ALDH1A1 (0.43) | ALDH1A1SLC1A3SLC1A2SLC1A1PIK3CD | |
| SCHEMBL23898801 | 0.98 | ALDH1A1 (0.43) | ALDH1A1SLC1A3SLC1A2SLC1A1PIK3CD | |
| SCHEMBL500153 | 0.80 | MEN1 (0.45) | ALDH1A1PIK3CDCHRM1MAPTHPGD | |
| Lithium Ion SCHEMBL30017453 | 0.78 | PIK3CD (0.36) | ALDH1A1PIK3CDCHRM1MAPTHPGD | |
| Lithium Ion SCHEMBL23886195 | 0.78 | PIK3CD (0.36) | ALDH1A1PIK3CDCHRM1MAPTHPGD | |
| SCHEMBL23886340 | 0.77 | ALDH1A1 (0.66) | ALDH1A1PIK3CDCHRM1MAPTHPGD | |
| SCHEMBL23886205 | 0.77 | ALDH1A1 (0.66) | ALDH1A1PIK3CDCHRM1MAPTHPGD | |
| SCHEMBL23886134 | 0.77 | ALDH1A1 (0.66) | ALDH1A1PIK3CDCHRM1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150981-A1 | N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-05-18 | — | — | US | disclosed |
| CN-115380030-A | N-heteroarylalkyl-2- (heterocyclyl and heterocyclylmethyl) acetamide derivatives as SSTR4 agonists | 武田药品工业株式会社 | 2022-11-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150981-A1 | N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS | SSTR4, SSTR3, SSTR5 | ALDH1A1 2983/4885SLC1A3 1002/4885SLC1A2 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.