SCHEMBL25189262

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25188550	0.85	LMNA (0.38)	LMNAGAAPRKCZL3MBTL1POLB
	SCHEMBL7219646	0.81	LMNA (0.54)	LMNAPRKCZDRD2L3MBTL1POLB
	SCHEMBL27335253	0.81	LMNA (0.41)	LMNAGAAABL1PRKCZL3MBTL1
	SCHEMBL25194820	0.80	ABL1 (0.42)	LMNAGAAABL1L3MBTL1HPGD
	SCHEMBL1976655	0.73	ABL1 (0.45)	LMNAGAAABL1L3MBTL1HPGD
	SCHEMBL29151120	0.73	ABL1 (0.45)	LMNAGAAABL1L3MBTL1POLB
	SCHEMBL30379588	0.72	POLB (0.53)	LMNAGAAL3MBTL1POLBTDP1
	SCHEMBL1976165	0.72	ABL1 (0.44)	LMNAGAAABL1L3MBTL1POLB
	SCHEMBL523584	0.72	ABL1 (0.57)	LMNAGAAABL1L3MBTL1POLB
	SCHEMBL23380498	0.70	ABL1 (0.45)	LMNAGAAABL1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.