Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.73 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207857 | 0.86 | KCNN3 (0.97) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL25187421 | 0.85 | KCNN3 (0.77) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL30421414 | 0.85 | KCNN3 (0.77) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL25191245 | 0.85 | KCNN3 (0.77) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL3233745 | 0.85 | KCNN3 (1.00) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL29355074 | 0.85 | KCNN3 (1.00) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL25203125 | 0.82 | KCNN2 (0.72) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL19686804 | 0.81 | KCNN3 (0.73) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL21165969 | 0.80 | KCNN2 (0.59) | KCNN2KCNN3ALOX15LMNANPSR1 | |
| SCHEMBL25188176 | 0.80 | KCNN3 (0.69) | KCNN2KCNN3ALOX15LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312333-B2 | SK channel positive allosteric modulators | CHAPMAN UNIVERSITY (US) | 2025-05-27 | — | — | US | disclosed |
| US-20230159500-A1 | SK CHANNEL POSITIVE ALLOSTERIC MODULATORS | CHAPMAN UNIVERSITY | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159500-A1 | SK CHANNEL POSITIVE ALLOSTERIC MODULATORS | KCNN1, KCNN4, KCNN2 | KCNN2 3/4885KCNN3 4/4885ALOX15 3494/4885 |
| US-12312333-B2 | SK channel positive allosteric modulators | KCNN1, KCNN4, KCNN2 | KCNN2 3/4885KCNN3 4/4885ALOX15 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.