SCHEMBL25189333

SCHEMBL25189333

O=C(/C=C/c1cccc(Cl)c1)c1ccc(N2CCC(O)CC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.59
▸ CA2 P00918 1/20 0.59
▸ MAOB P27338 7/20 0.59
▸ MAPT P10636 5/20 0.57
▸ NPC1 O15118 3/20 0.57
▸ RAB9A P51151 3/20 0.57
▸ HDAC3 O15379 2/20 0.56
▸ HDAC4 P56524 2/20 0.56
▸ HDAC1 Q13547 2/20 0.56
▸ HDAC7 Q8WUI4 2/20 0.56
▸ HDAC2 Q92769 2/20 0.56
▸ HDAC10 Q969S8 2/20 0.56
▸ HDAC11 Q96DB2 2/20 0.56
▸ HDAC8 Q9BY41 2/20 0.56
▸ HDAC6 Q9UBN7 2/20 0.56
▸ HDAC9 Q9UKV0 2/20 0.56
▸ HDAC5 Q9UQL6 2/20 0.56
▸ MAOA P21397 3/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25208894 1.00 CA1 (0.59) CA1CA2MAOBMAPTNPC1
SCHEMBL31233292 1.00 CA1 (0.59) CA1CA2MAOBMAPTNPC1
SCHEMBL30384395 1.00 CA1 (0.59) CA1CA2MAOBMAPTNPC1
SCHEMBL25216238 0.87 MAPT (0.74) MAOBMAPTNPC1RAB9AHDAC3
SCHEMBL25200446 0.87 MAPT (0.74) MAOBMAPTNPC1RAB9AHDAC3
SCHEMBL30382887 0.87 MAPT (0.74) MAOBMAPTNPC1RAB9AHDAC3
SCHEMBL30383968 0.87 MAPT (0.74) MAOBMAPTNPC1RAB9AHDAC3
SCHEMBL25208497 0.86 MAPT (0.75) MAOBMAPTNPC1RAB9AHDAC3
SCHEMBL25200405 0.86 HDAC3 (0.59) CA1CA2MAOBMAPTNPC1
SCHEMBL25195512 0.86 HDAC3 (0.59) CA1CA2MAOBMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CA1 4078/4885CA2 2635/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CA1 3374/4885CA2 2843/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CA1 3374/4885CA2 2843/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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