SCHEMBL25190741

SCHEMBL25190741

COCCNc1cc(NC(=O)c2cn(C)c3cc(Br)c(C=O)nc23)ncc1C#N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25193340 0.90 FGFR4 (1.00) FGFR4
SCHEMBL30386454 0.87 FGFR4 (1.00) FGFR4
SCHEMBL25190219 0.87 FGFR4 (1.00) FGFR4
SCHEMBL25213721 0.86 FGFR4 (0.78) FGFR4
SCHEMBL30386346 0.86 FGFR4 (0.78) FGFR4
SCHEMBL25187976 0.86 FGFR4 (1.00) FGFR4
SCHEMBL30385803 0.86 FGFR4 (1.00) FGFR4
SCHEMBL25189852 0.86 FGFR4 (1.00) FGFR4
SCHEMBL25188672 0.86 FGFR4 (1.00) FGFR4
SCHEMBL25199943 0.86 FGFR4 (1.00) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO claimed
CN-116102549-B 5-Aldehyde heterocyclic amide compound and application thereof 暨南大学 2025-02-11 — — CN disclosed
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO disclosed
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO disclosed
CN-116102549-A 5-aldehyde heterocyclic amide compound and application thereof 暨南大学 2023-05-12 — — CN disclosed
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