SCHEMBL25193340

SCHEMBL25193340

COCCNc1cc(NC(=O)c2cn(C(C)C)c3cc(Br)c(C=O)nc23)ncc1C#N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25190741 0.90 FGFR4 (1.00) FGFR4
SCHEMBL25187980 0.87 FGFR4 (0.81) FGFR4
SCHEMBL30386158 0.87 FGFR4 (0.81) FGFR4
SCHEMBL25187795 0.86 FGFR4 (0.76) FGFR4
SCHEMBL30385528 0.85 FGFR4 (1.00) FGFR4
SCHEMBL25201462 0.85 FGFR4 (1.00) FGFR4
SCHEMBL25491355 0.85 FGFR4 (0.86) FGFR4
SCHEMBL25436590 0.84 FGFR4 (0.80) FGFR4
SCHEMBL25491356 0.84 FGFR4 (0.80) FGFR4
SCHEMBL25190426 0.83 FGFR4 (1.00) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102549-B 5-Aldehyde heterocyclic amide compound and application thereof 暨南大学 2025-02-11 — — CN claimed
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO claimed
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO disclosed
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