SCHEMBL25191295

SCHEMBL25191295

COc1cc(/C=C/C(=O)c2ccccc2OC)ccc1O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.85
PTGS2 P35354 1/20 0.85
CXCL12 P48061 7/20 0.79
ABCG2 Q9UNQ0 2/20 0.76
MAOB P27338 2/20 0.71
ACHE P22303 1/20 0.71
CHRNA7 P36544 1/20 0.71
MAOA P21397 1/20 0.70
NFKB1 P19838 2/20 0.70
NFKB2 Q00653 2/20 0.70
RELA Q04206 2/20 0.70
MEN1 O00255 1/20 0.70
KMT2A Q03164 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
AR P10275 1/20 0.68
CYP1A2 P05177 1/20 0.67
ALOX5 P09917 1/20 0.67
CYP2D6 P10635 1/20 0.67
HSD11B1 P28845 1/20 0.67
STAT3 P40763 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396596 0.92 PTGS1 (1.00) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL3396591 0.92 PTGS1 (1.00) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL29427953 0.92 PTGS1 (1.00) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL25195740 0.92 PTGS1 (1.00) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL23951755 0.92 ABCG2 (0.76) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL25266095 0.92 ABCG2 (0.76) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL31233136 0.92 ABCG2 (0.76) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL25195162 0.89 PTGS1 (0.81) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL31233232 0.89 ABCG2 (0.76) PTGS1PTGS2CXCL12ABCG2MAOB
SCHEMBL25191764 0.89 ABCG2 (0.76) PTGS1PTGS2CXCL12ABCG2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B PTGS1 522/4885PTGS2 704/4885CXCL12 399/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 PTGS1 180/4885PTGS2 330/4885CXCL12 287/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 PTGS1 180/4885PTGS2 330/4885CXCL12 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.