Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.52 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119827 | 0.87 | CHRM1 (0.65) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL28976379 | 0.85 | CHRM1 (0.62) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Ammonia Solution, Strong SCHEMBL28268974 | 0.85 | CHRM1 (0.62) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL8816437 | 0.85 | CHRM1 (0.67) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Propionic Acid SCHEMBL23044698 | 0.83 | ADRA2A (0.61) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Propionic Acid SCHEMBL19617436 | 0.82 | ADRA2A (0.59) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL28638398 | 0.82 | CHRM1 (0.79) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Propionic Acid SCHEMBL23044732 | 0.77 | CHRM1 (0.48) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL2303835 | 0.76 | ADRA2A (0.70) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL9022612 | 0.75 | CHRM1 (0.56) | CHRM1CHRM3CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083322-A1 | TRANSDERMALLY ADMINISTERED FORMULATION MATERIAL, PHARMACEUTICAL FORMULATION FOR REALIZING NUCLEIC ACID SKIN DELIVERY, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉瑞佶生物科技有限公司 | 2023-05-19 | — | — | WO | claimed |