Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 4/20 | 0.43 |
| ▸ | JAK1 | P23458 | 4/20 | 0.43 |
| ▸ | TYK2 | P29597 | 4/20 | 0.43 |
| ▸ | RET | P07949 | 6/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25417203 | 0.87 | CHEK1 (0.43) | PIM1CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL25417690 | 0.81 | JAK2 (0.53) | PIM1CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL25419024 | 0.78 | BTK (0.58) | JAK2JAK1TYK2RETJAK3 | |
| SCHEMBL25418779 | 0.77 | JAK2 (0.52) | PIM1JAK2JAK1TYK2PIM3 | |
| SCHEMBL24438930 | 0.77 | BTK (0.43) | PIM1CHEK1JAK2JAK1TYK2 | |
| SCHEMBL19300148 | 0.76 | JAK2 (0.48) | PIM1CHEK1JAK2JAK1TYK2 | |
| SCHEMBL19253538 | 0.74 | JAK2 (0.47) | CHEK1JAK2JAK1TYK2RET | |
| SCHEMBL19253460 | 0.74 | JAK2 (0.47) | JAK2JAK1TYK2RETJAK3 | |
| SCHEMBL24439168 | 0.72 | JAK2 (0.47) | JAK2JAK1TYK2RETAURKB | |
| SCHEMBL25201129 | 0.71 | JAK2 (0.46) | JAK2JAK1TYK2RETJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250090524-A1 | BTK INHIBITORS | BIOGEN MA INC. | 2025-03-20 | — | — | US | disclosed |
| CN-118984829-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2024-11-19 | — | — | CN | disclosed |
| EP-4430048-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086575-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086575-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250090524-A1 | BTK INHIBITORS | BTK, SYK, LYN | PIM1 62/4885CHEK1 342/4885CCNA2 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.