SCHEMBL25194893

SCHEMBL25194893

O=C(O)C=Cc1ccc(/C=C/C(=O)c2ccccc2O)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.83
▸ CYP2C19 P33261 2/20 0.83
▸ BCHE P06276 2/20 0.83
▸ MAOB P27338 7/20 0.78
▸ MAOA P21397 6/20 0.78
▸ MAPK1 P28482 4/20 0.78
▸ KMT2A Q03164 4/20 0.78
▸ KDM4E B2RXH2 3/20 0.78
▸ MEN1 O00255 3/20 0.78
▸ TDP1 Q9NUW8 3/20 0.78
▸ ALDH1A1 P00352 3/20 0.78
▸ CYP3A4 P08684 2/20 0.78
▸ HPGD P15428 2/20 0.78
▸ ALOX15 P16050 2/20 0.78
▸ SMN1; SMN2 Q16637 2/20 0.78
▸ TP53 P04637 1/20 0.78
▸ ALOX12 P18054 1/20 0.78
▸ GAA P10253 1/20 0.69
▸ PTGS1 P23219 1/20 0.69
▸ PTGS2 P35354 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25233412 0.93 MAOB (0.89) MAPTCYP2C19BCHEMAOBMAOA
SCHEMBL25191373 0.93 MAOB (0.89) MAPTCYP2C19BCHEMAOBMAOA
SCHEMBL25219836 0.93 MAOB (0.89) MAPTCYP2C19BCHEMAOBMAOA
SCHEMBL25195966 0.93 MAOB (0.89) MAPTCYP2C19BCHEMAOBMAOA
2'-Hydroxychalcone SCHEMBL30533458 0.91 MAPT (1.00) MAPTCYP2C19BCHEMAOBMAOA
2'-Hydroxychalcone SCHEMBL126857 0.91 MAPT (1.00) MAPTCYP2C19BCHEMAOBMAOA
2'-Hydroxychalcone SCHEMBL30383374 0.91 MAPT (1.00) MAPTCYP2C19BCHEMAOBMAOA
2'-Hydroxychalcone SCHEMBL25198692 0.91 MAPT (1.00) MAPTCYP2C19BCHEMAOBMAOA
2'-Hydroxychalcone SCHEMBL679661 0.91 MAPT (1.00) MAPTCYP2C19BCHEMAOBMAOA
2'-Hydroxychalcone SCHEMBL30456521 0.91 MAPT (1.00) MAPTCYP2C19BCHEMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885CYP2C19 109/4885BCHE 588/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885CYP2C19 583/4885BCHE 465/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885CYP2C19 583/4885BCHE 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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