SCHEMBL25195558

SCHEMBL25195558

CCOc1ccc(C(=O)/C=C/c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 11/20 0.81
▸ MAPT P10636 3/20 0.81
▸ MAOA P21397 1/20 0.81
▸ NPC1 O15118 1/20 0.81
▸ RAB9A P51151 1/20 0.81
▸ KMT2A Q03164 1/20 0.81
▸ ABCG2 Q9UNQ0 2/20 0.79
▸ KDM4E B2RXH2 2/20 0.73
▸ LMNA P02545 2/20 0.73
▸ POLB P06746 1/20 0.73
▸ NPSR1 Q6W5P4 1/20 0.73
▸ CYP1A1 P04798 1/20 0.71
▸ CYP1B1 Q16678 1/20 0.71
▸ XDH P47989 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776503 0.90 MAPT (1.00) MAOBMAPTMAOANPC1RAB9A
SCHEMBL11776508 0.90 MAPT (1.00) MAOBMAPTMAOANPC1RAB9A
SCHEMBL20551930 0.90 MAOB (1.00) MAOBMAPTMAOANPC1RAB9A
SCHEMBL25214471 0.89 ABCG2 (0.80) MAOBMAPTMAOANPC1RAB9A
SCHEMBL25194910 0.89 MAOB (0.77) MAOBMAPTMAOANPC1RAB9A
SCHEMBL25202067 0.89 MAOB (0.77) MAOBMAPTMAOANPC1RAB9A
SCHEMBL25201231 0.88 MAOB (1.00) MAOBMAPTMAOANPC1RAB9A
SCHEMBL9818322 0.88 MAOB (1.00) MAOBMAPTMAOANPC1RAB9A
SCHEMBL14588244 0.88 MAOB (1.00) MAOBMAPTMAOANPC1RAB9A
SCHEMBL25205390 0.88 MAOB (1.00) MAOBMAPTMAOANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885MAPT 3297/4885MAOA 1902/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAPT 3512/4885MAOA 3145/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAPT 3512/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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