SCHEMBL25196319

SCHEMBL25196319

O=C(/C=C/c1ccccc1)c1ccc(C(=O)OCCCCCCO)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 10/20 0.55
ACHE P22303 9/20 0.55
CYP1B1 Q16678 7/20 0.54
MAOB P27338 4/20 0.54
MAPT P10636 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
TNFRSF1A P19438 2/20 0.54
PLIN1 O60240 1/20 0.54
LMNA P02545 1/20 0.54
RECQL P46063 1/20 0.54
PLIN5 Q00G26 1/20 0.54
ABHD5 Q8WTS1 1/20 0.54
MEN1 O00255 2/20 0.52
HSPD1 P10809 2/20 0.52
MAOA P21397 2/20 0.52
HSPE1 P61604 2/20 0.52
KMT2A Q03164 2/20 0.52
ALDH2 P05091 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP19A1 P11511 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27517367 0.96 TDP1 (0.56) BCHEACHECYP1B1MAOBMAPT
SCHEMBL7056394 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL7058893 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL7056399 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL2996225 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL14634858 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL2996226 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL14634860 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL7058896 0.85 BCHE (0.73) BCHEACHEMAOBMAOA
SCHEMBL3005012 0.84 BCHE (0.73) BCHEACHEMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 BCHE 465/4885ACHE 656/4885CYP1B1 1027/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 BCHE 465/4885ACHE 656/4885CYP1B1 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.