Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 16/20 | 0.52 |
| ▸ | HTR2C | P28335 | 16/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956781 | 1.00 | HTR2A (0.52) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL25188793 | 0.82 | HTR2A (0.55) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL6034623 | 0.78 | HTR2A (0.72) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL25187258 | 0.72 | HTR2A (0.44) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL30956782 | 0.72 | HTR2A (0.44) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL6034633 | 0.71 | HTR2A (0.60) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL25301879 | 0.70 | ENPP2 (0.47) | GAA | |
| SCHEMBL6598163 | 0.69 | HTR2A (0.60) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL25190283 | 0.68 | HTR2A (0.40) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL30989170 | 0.67 | TSHR (0.48) | ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201922-A | Drak2 inhibitor and preparation method and application thereof | 百极优棠(广东)医药科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023083330-A1 | DRAK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 百极优棠(广东)医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |
| WO-2023083330-A1 | DRAK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 百极优棠(广东)医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |