SCHEMBL25197837

SCHEMBL25197837

C=CCc1ccc(/C=C/C(=O)c2ccc(CO)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 3/20 0.51
MAPT P10636 5/20 0.50
TNFRSF1A P19438 2/20 0.50
MAOB P27338 6/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC2 Q92769 1/20 0.48
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAOA P21397 3/20 0.45
RAB9A P51151 2/20 0.45
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
CXCL12 P48061 1/20 0.45
POLB P06746 1/20 0.45
CYP1B1 Q16678 2/20 0.45
PLIN1 O60240 1/20 0.45
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25193984 0.89 F3 (0.63) F3MAPTTNFRSF1AMAOBHDAC8
SCHEMBL1481590 0.83 F3 (0.56) F3MAPTTNFRSF1AMAOBHDAC8
SCHEMBL1481587 0.83 F3 (0.56) F3MAPTTNFRSF1AMAOBHDAC8
SCHEMBL25191042 0.83 F3 (0.77) F3MAPTMAOBLMNAMAOA
SCHEMBL13641563 0.83 F3 (0.77) F3MAPTMAOBLMNAMAOA
SCHEMBL1481611 0.81 F3 (0.54) F3MAPTTNFRSF1AMAOBHDAC8
SCHEMBL1481606 0.81 F3 (0.54) F3MAPTTNFRSF1AMAOBHDAC8
SCHEMBL15631515 0.81 MAPT (0.77) F3MAPTTNFRSF1AMAOBLMNA
SCHEMBL25232470 0.81 MAPT (0.70) F3MAPTTNFRSF1AMAOBHDAC8
SCHEMBL25195200 0.81 CYP1B1 (0.70) F3MAPTTNFRSF1AMAOBHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B F3 5/4885MAPT 3297/4885TNFRSF1A 2669/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885TNFRSF1A 3485/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885TNFRSF1A 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.