SCHEMBL25198530

SCHEMBL25198530

O=C(/C=C/c1ccc(/C=C2\SC(=S)N(C(Cc3ccccc3)C(=O)O)C2=O)cc1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.77
▸ MME P08473 2/20 0.76
▸ BCL2L2 Q92843 6/20 0.73
▸ BCL2 P10415 5/20 0.73
▸ BAD Q92934 5/20 0.73
▸ POLB P06746 3/20 0.73
▸ PLA2G1B P04054 1/20 0.73
▸ ATG4B Q9Y4P1 1/20 0.73
▸ MEN1 O00255 5/20 0.69
▸ KMT2A Q03164 5/20 0.69
▸ ALDH1A1 P00352 5/20 0.69
▸ CRHBP P24387 1/20 0.69
▸ CRHR2 Q13324 1/20 0.69
▸ L3MBTL1 Q9Y468 1/20 0.69
▸ DUSP3 P51452 1/20 0.66
▸ NPC1 O15118 1/20 0.64
▸ ADAMTS5 Q9UNA0 1/20 0.64
▸ MAPK1 P28482 1/20 0.62
▸ RECQL P46063 1/20 0.62
▸ CTSL P07711 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25198529 1.00 MAPT (0.77) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25200467 0.94 MME (0.73) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25265299 0.94 MAPT (0.82) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25198109 0.94 BCL2L2 (0.82) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25185087 0.94 MME (0.73) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25188655 0.94 MAPT (0.82) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25265304 0.94 BCL2L2 (0.82) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25185088 0.94 MME (0.73) MAPTMMEBCL2L2BCL2BAD
SCHEMBL25265368 0.94 MME (0.73) MAPTMMEBCL2L2BCL2BAD
SCHEMBL28520077 0.92 BCL2L2 (0.73) MAPTMMEBCL2L2BCL2BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MME 322/4885BCL2L2 992/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MME 131/4885BCL2L2 1431/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MME 131/4885BCL2L2 1431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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