SCHEMBL25199541

SCHEMBL25199541

CC(=O)Nc1ccc(C=CC(=O)c2ccc(OCC(=O)O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.66
KMT2A Q03164 4/20 0.66
RAB9A P51151 4/20 0.66
MEN1 O00255 3/20 0.66
NPC1 O15118 3/20 0.66
MAPK1 P28482 1/20 0.66
POLB P06746 1/20 0.58
BLM P54132 1/20 0.58
GPR35 Q9HC97 1/20 0.58
MAOB P27338 8/20 0.54
MAOA P21397 1/20 0.54
ABCG2 Q9UNQ0 2/20 0.53
ALDH1A1 P00352 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25195104 1.00 MAPT (0.66) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL25195488 1.00 MAPT (0.66) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL11459733 0.87 KMT2A (0.75) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL11459734 0.87 KMT2A (0.75) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL25208390 0.85 KMT2A (0.56) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL25214787 0.84 NPC1 (0.71) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL25194910 0.83 MAOB (0.77) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL25206233 0.83 MAOB (0.75) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL25217929 0.83 MAOB (0.75) MAPTKMT2ARAB9AMEN1NPC1
SCHEMBL25202067 0.83 MAOB (0.77) MAPTKMT2ARAB9AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KMT2A 3188/4885RAB9A 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.